Pre2MedX

Pre²Med X-Portal is an academic web server designed to support cancer precision therapy research through transcriptomics-based prediction of drug response and immunotherapy potential. The platform provides a unified and standardized analytical environment for integrative analysis of both single-cell and bulk RNA-seq data using multiple established predictive models.

Pre²Med X-Portal enables users to perform multi-model drug response prediction for small-molecule anticancer therapies, capture cellular heterogeneity at the single-cell level, and assess immunotherapy response potential based on tumor-intrinsic and tumor microenvironment-associated transcriptomic features. By combining standardized data processing workflows, parallel model execution, interactive visualization, and consolidated result reporting, Pre²Med X-Portal offers a one-stop solution for translational cancer research and precision treatment.

scRNA-seq

The scRNA-seq module enables drug response prediction at single-cell resolution, allowing users to characterize cellular heterogeneity, prioritize candidate drugs, and identify potential combination strategies by resolving drug-sensitive and drug-resistant subpopulations within complex tumor samples.

bulk RNA-seq

The bulk RNA-seq module supports population-level drug response prediction, enabling systematic prioritization of candidate anticancer drugs and exploration of potential combination strategies based on inferred therapeutic sensitivity and resistance patterns.

ICB

The ICB module provides immunotherapy response inference, enabling assessment of potential benefit from immune checkpoint blockade based on tumor-intrinsic and tumor microenvironment-associated expression features.

Pre2Med X-Portal An integrated web server for transcriptomics-based drug response and immunotherapy prediction in cancer

Pre²Med X-Portal
An integrated web server for transcriptomics-based drug response and immunotherapy prediction in cancer